K. Sternberg
Advanced professor (W2 with conversion to W3) to the Rostock University on the subject of "Biomedical technology" as part of the professorship programme of the federal government and the states for the promotion of equality of women and men in Science and Research at German universities

S. Barcikowski
W3 Technical chemistry, University of Duisburg-Essen

T. Stöver
W3 Otolaryngology, KGU Frankfurt/Main

B. Chichkov
Rebirth W3 Professor Nanoengineering, Leibniz University Hannover, Institute for Quantum Optics

S. Jockenhövel
Joint professorship (W2 with conversion to W3) at the RWTH Aachen

A Heisterkamp
W2

A. Heisterkamp, LUH: Titel: Method and system for the manipulation of cells Applicants: Gottfried Wilhelm Leibniz Universität Hannover; Harvard College, ref: 23.02-02-02126/2, eingereicht.

Barcikowski, S. et al.: „Implantat und Verfahren zu dessen Herstellung" Patent-Anmeldung WO 2009/000550-A2 vom 31.12.2008

Simon Höges, Konrad Wissenbach, Rüdiger Blindt: „Vorrichtung zur schichtweisen Fertigung von Bauteilen, sowie Verfahren zur schichtweisen Fertigung von Bauteilen". Antrag auf Erteilung eines Patents am 22.02.2010

Schmidt W, Sternberg K, Behrend D, Guthoff R and Schmitz KP: Augenimplantat. 2007: DE 10 2007 004 906A1 (Offenlegungsschrift, in Prüfung), dazu auch WO002008090225A1 und US 2009/0326432 A1.

A. Hahn
Poster prize at the international 8th Fall Ruber Colloquium [Kautschuk-Herbst-Kolloquium] 2008 "Novel functionalised laser generated nanoparticles for innovative polymers"

G. Paasche
The winner of the Innovation Competition for Medical Technology in 2009 from the Federal Ministry of Education and Research (BMBF) "Nanostructured electrodes for electrical characterisation as well as manipulation of cells."

The RWTH Aachen has set up a joint professorship between Medicine and Engineering Science as the result of work from the special research area of SFB/Transregio 37.

The medical engineering of the present represents an extremely complex, multidisciplinary research area which offers incredible development opportunities in the intensive combination of medicine, engineering, computer science and natural science. The micro and nanosystem technology is here the key technology. In minimally invasive diagnostics, in the therapy and therapy control, in the development of implants or medication dispensing systems, the micro and nano technology components are essential building blocks of the entire system. In the course of the continually advancing extreme miniaturisation of individual components, the use of the smaller, more active implants for medical applications offers more and more also in ophthalmology. In this special issue, three very innovative projects are presented, from our point of view, in the area of active implants in ophthalmology which work with problems to be solved in a multidisciplinary manner.

Rostock scientists study therapeutic potential of human stem cells from different tissues

Even if they have the same phenotypical characteristics with regard to the therapeutic potential, stem cells from different sources differ significantly from each other. For a stem cell therapy after a heart infarct – that is what researchers from the Rostock University have first systematically determined - stem cells from bone marrow are the most effective, stem cells from umbilical cord blood contribute the least to the healing processes. The study appears in the 11th February edition of the journal "PLoS one".

Prof. Steinhoff und Dr. Kaminski wurden von einem Journalisten der dpa interviewt. Dabei wurde auch die Zusammenarbeit im SFB angesprochen. Die daraus entstandenen Presseartikel sind in der folgenden Form online zu finden (unvollständige Liste):

Roock A, Hahn A, Barcikowski S, Wulf K, Ceschi P, Paasche G, Lenarz T, Schmitz KP, Sternberg K. Specific surface modification of silicone-based cochlear implant electrode carriers for fibrosis prevention and spiral ganglion cell enhancement. Biomed Tech.in press. 2011.

Dunda SE, Schriever T, Rosen C, Tolba RH, Diamantouros S, Jockenhoevel S, Pallua N. A new approach of in vivo musculoskeletal tissue engineering using the epigastric artery as central core vessel of 3-dimensional construct. Plastic Surgery International.in press. 2012.

Willenbrock S, Braun O, Baumgart J, Lange S, Junghanss C, Heisterkamp A, Nolte I, Bullerdiek J, Murua Escobar H. TNF-a stimulation triggers release of high mobility group box 1 (HMGB1) protein in mammary cells (MTH53A) of epithelial origin. Cytokine.57:210-20. 2012.

Hahn A, Fuhlrott J, Loos A, Barcikowski S. Cytotoxicity and ion release of alloy nanoparticles. J Nanopart Res.14:686. 2012.

Willenbrock S, Knippenberg S, Meier M, Hass R, Wefstaedt P, Nolte I, Murua Escobar H, Petri S. In vivo MRI of Intraspinally Injected SPIO-labelled Human CD34+ Cells in a Transgenic ALS Mouse Model of ALS. In Vivo.26:31-8. 2012.

Prakasam RK, Schwiede M, Hutz WW, Guthoff RF, Stachs O. Corneal Responses to Eye Rubbing with Spectral Domain Optical Coherence Tomography. Curr Eye Res.37:25-32. 2012.

Leyh RG, Wilhelmi M, Rebe P, Ciboutari S, Haverich A, Mertsching H. Tissue engineering of viable pulmonary arteries for surgical correction of congenital heart defects. Ann Thorac Surg. 2006 Apr;81(4):1466-70; discussion 1470-1.

Glasmacher B., Autschbach R., Voigt P., Welte T., Wilhelmi M.: Aspects of cardiovascular bio-materials. BIOmaterialien 2007, 8(3), 134 (Abstract)

Glasmacher B., Vienken J.: Biomaterialien im Spagat zwischen Forschung und Anwendung. Chemie Ingenieur Technik 2007; 79(9): 1380 (Abstract)

Kruse L., Vasilic K., Modigell M., Glasmacher B.(2007): "Biomaterial-induced blood damage at defined shear stress". BIOmaterialien 8(3), 229 (1st. Poster Award)

Vasilic K., Kruse L., Glasmacher B., Modigell M.: Prediction of mechanical blood damage in extracorporeal devices. Chemie Ingenieur Technik 79 (2007) 9, S. 1380-1381 (Abstract)

Hahn A.;Stöver T.; Paasche G.; Gomez P. ;Löbler M.; Sternberg K.; Rohm H.; .Schmitz K.P.; Barcikowski S.: Bioactive nanocomposites from laser ablation in liquids adapted to cell specific concentration levels. Biomaterialien;9 (2008) 3/4 2008; S: 124-124

J. Ilgner, S. Biedron, D. Klee, M. Löbler, S. Gabriel, M. Westhofen. Grundlagen zu Beschichtungsverfahren von Titan-Mittelohrprothesen zur Steuerung der Gewebeinteraktion. Westdeutscher HNO-Kongress 2008, Solingen

Kruse L. Modigell M., Glasmacher B. (2008): "Platelet activation and hemolysis by high shear stress". Int J Artif Organs 31(7): 630

Kruse L., Moll A., Modigell M., Glasmacher B.: In vitro hemocompatibility testing of varied geometries in a high shear blood flow. BIOmaterialien 2008, 9(3/4), 134 (Abstract)

Ovsianikov A.; Obata K.; Schlie S.; Chichkow B. ;Löbler M.;Sternberg K.; Schmitz K.P.:Photostructured Poly(Ethylene Glycol)-based materials for biomedical applications. Biomaterialien;9 (2008) 3/4 2008; S: 125-125

Buss, D., Löbler, M., Schmidt, W., Stachs, O., Wree, A., Guthoff, R., Schmitz K.-P. (2009): Analysis of fibroblasts of the suprachoroidal space for development of a new glaucoma micro stent. IFMBE Proceedings 25/XI, p. 153 ff.

Fuhlrott J., Loos A., Glasmacher B., Löbler M. (2009):„Endozytose und Zytotoxizität von Nanopartikeln", BioMaterialien 10 (3/4):109

Luderer, F., Sternberg, K., Rohm, H.W., Löbler, M., Köck, K., Kroemer, H.K., Schmitz, K.-P. (2009): Biodegradable Sirolimus-loaded Poly(lactide) Nanoparticles as Delivery Systems for the Prevention of Restenosis in Coronary Stent Application. IFMBE Proceedings 25/X, p. 193 ff.

Rohm, H.W., Perrier, T., Lautram, N., Schmitz, K.-P., Saulnier, P., Löbler, M. (2009):Fate of drug loaded-LNCs in cell culture medium - impact on drug delivery strategies. IFMBE Pro-ceedings 25/VIII, p. 65 ff.

Sternberg, K., Löbler, M., Stachs, O., Schmidt, W., Guthoff, R., Schmitz, K.-P. (2010):Local drug delivery concepts and surface modification in glaucoma implant surgery. Nova Acta Leopoldina 111 (379):95-104

Sternberg, K., Terwee, T., Stachs, O., Guthoff, R., Löbler, M., Schmitz, K.-P. (2010).Drug-induced secondary cataract prevention – Experimental ex vivo and in vivo results with Disul-firam, Methotrexate and Actinomycin D –Ophthalmic Res., im Druck

Evertz F., Glasmacher B., Kietzmann M., Müller P.P., Hauser H.: Evaluation of Magnesium alloys as degradable implant material; eingereicht für 37. Annual meeting European Society for Artificial Organs (ESAO), Skopje, Macedonia, 8.-11. September 2010

Heinrich A, Löbler M., Schmitz K.-P., Guthoff R. F (2010):"Genexpression zur Charakterisierung von Fibroblasten im Rahmen der Glaukomchirurgie". 59.Tagung der Vereinigung Norddeutscher Augenärzte, 23.-24. April 2010 in Göttingen.

Glasmacher B, Vienken, J: Neue Implantate: Funktionalität versus Regeneration. Chemie Ingenieur Technik 2010, 82,(9): 1367 (DOI: 10.,1002/cite.201050031)

Zweigerdt R, Olmer R, Singh H, Haverich A, Martin U. Scalable expansion of human pluripotent stem cells in suspension culture. Nat Protoc. 2011 Apr;6(5):689-700. Epub 2011 Apr 2

Löbler M, Rehmer A, Guthoff R, Martin H, Sternberg K, Stachs O (2011): Suitability and calibration of a rebound tonometer to measure IOP in rabbit and pig eyes. Vet Ophthalmol 14:66-68

Löbler, M., Sternberg, K., Stachs, O., Allemann, R., Grabow, N., Roock, A., Kreiner, CF., Streufert, D., Neffe, AT., Hanh, BD., Lendlein, A., Schmitz, KP., Guthoff, R. (2011): Polymers and drugs suitable for the development of a drug delivery drainage system in glaucoma surgery. J. Biomed. Mater Res. Part B. 97:388-395

Ovsianikov, A., Malinauskas, M., Schlie, S., Ngezahayo, A., Gittard, S., Narayan, R., Löbler, M., Sternberg, K., Schmitz, K.-P., Haverich, A., Chichkov, B. N. (2011): Three-dimensional laser micro- and nano-structuring of acrylated poly(ethylene glycol) materials and evaluation of their cytoxicity for tissue engineering applications. Acta Biomaterialia 7:967-974

Paasche, G., Ceschi, P., Löbler, M., Rösl, C., Gomes, P., Hahn, A., Rohm, HW., Sternberg, K., Lenarz, T., Schmitz, KP., Barcikowski, S., Stöver, T. (2011): Protective and toxic effects of metal ions on spiral ganglion cells and fibroblasts. J. Neurosci. Res. 89:611-617